Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. [ GOC : mtg_transport https://www.worldcat.org/search?q=bn%3A0815340729 ]
ATP-coupled transmembrane transporter activity
ATP-dependent transmembrane transporter activity
ATPase activity, coupled to transmembrane movement of substances
Term information
- Reactome:R-HSA-9033505 (PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12)
- Reactome:R-HSA-9033499 (PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol)
- Reactome:R-HSA-2161538 (abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate)
- Reactome:R-HSA-2161506 (abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate)
- Reactome:R-HSA-1467457 (ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region)
- GO:0043492
- GO:0015405
- GO:0016820
- P-P-bond-hydrolysis-driven transporter
- ATPase activity, coupled to movement of substances
- P-P-bond-hydrolysis-driven transmembrane transporter activity
- hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- molecular_function
- GO:0042626
- https://github.com/geneontology/go-ontology/issues/17373
- https://github.com/geneontology/go-ontology/issues/14642
- https://github.com/geneontology/go-ontology/issues/19965