The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.

A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.

A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.

Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.

Binding to interleukin-35.

Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.

Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity.

Any process that stops or reduces the activity of a phosphoprotein phosphatase.

Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity.

Any process that activates or increases the activity of a phosphoprotein phosphatase.

Binding to an interleukin-35 receptor.

Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I.

Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.

A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.

A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.

Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+.