A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.

A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).

OBSOLETE. Binding to an isoform of the MDM2 protein, a negative regulator of p53.

A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.

A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.

OBSOLETE. Binding to an isoform of the MDM4 protein, a negative regulator of p53.

The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.

Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell.

Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell.

Any process involved in the maintenance of an internal steady state of divalent inorganic anions at the level of a cell.

Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell.

The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.

A protein complex that possesses alpha-ketoglutarate dehydrogenase activity.

Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity.

The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.

The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.

The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.

The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.

The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.

OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle.