Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.

Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity.

Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.

A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle.

Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity.

Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell.

Any process that decreases the frequency, rate or extent of erythrocyte enucleation.

Any process that modulates the frequency, rate or extent of erythrocyte enucleation.

Any process that increases the frequency, rate or extent of erythrocyte enucleation.

The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.

The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes.

Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.

Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.

A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.

Any process that modulates the rate frequency or extent of c-di-GMP signaling.

Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.

Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.

Any process that decreases the rate, frequency or extent of c-di-GMP signaling.

Any process that increases the rate, frequency or extent of c-di-GMP signaling.

The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.