The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.

The somatic process that results in the generation of sequence diversity of immunoglobulins.

The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.

The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.

The process in which immune receptor genes are diversified through somatic mutation.

The process in which immune receptor genes are diversified through gene conversion.

Recombination occurring within or between DNA molecules in somatic cells.

The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.

The process in which immune receptor genes are diversified through alternate splicing.

The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.

A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.

The regulated exocytosis of secretory granules by a leukocyte.

Any process involved in the carrying out of an immune response by a basophil.

The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.

Fusion of an endocytosed synaptic vesicle with an endosome.

Fusion of a synaptic vesicle with an endosome.

An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.

An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.

An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.

Any process involved in the carrying out of an immune response by a mast cell.