The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.

Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.

Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol.

Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone.

Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+).

Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.

Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O.

Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose.

OBSOLETE. Any protein binding that is involved in negative regulation of telomere maintenance via telomerase.

Any process that activates or increases the frequency, rate or extent of protein autoubiquitination.

The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.

The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.

The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.

The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.

Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.

Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.

Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation.

The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.

The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.