Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.

The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.

Any process by which the numbers of cells of a particular type or in a tissue are maintained.

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.

Binds to and stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.

OBSOLETE. (Was not defined before being made obsolete).

OBSOLETE. (Was not defined before being made obsolete).

OBSOLETE. (Was not defined before being made obsolete).

OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation.

Binds to and stops, prevents or reduces the activity of phospholipase A2.

Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.

The rupture of cell membranes and the loss of cytoplasm.

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.

The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.

OBSOLETE. (Was not defined before being made obsolete).

Binding to a growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.

The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.